REFINE welcomes The Cyprus Institute of Neurology & Genetics (CING) as a new consortium partner through the Horizon Europe Hop-On Facility.

CING joined REFINE on 1 April 2026 and will lead a newly added work package: WP10 – Computational Integration for Virus-Host Targeting and Therapeutic Discovery. This new work package will strengthen REFINE’s capacity to integrate experimental and computational approaches to identify new therapeutic strategies against orthoflaviviruses.

Within REFINE, CING will provide expertise in host-pathogen interaction networks, computational modelling, and graph-based prediction of drug synergies. These contributions will support virus-host target identification and guide experimental validation across the consortium. WP10 will collaborate closely with existing scientific work packages, ensuring effective feedback between data generation, computational analysis, and laboratory validation.

CING also brings strong expertise in molecular virology and West Nile virus research in Cyprus. Its participation will broaden REFINE’s geographical scope and further strengthen the consortium’s ability to address orthoflavivirus infections from complementary scientific and regional perspectives.

The inclusion of CING through the Hop-On Facility adds new expertise, infrastructure and research capacity to REFINE. It will enhance the project’s integrative approach and support its overall ambition to develop receptor-focused interventions against orthoflavivirus neuroinvasion and entry.